Please enable JavaScript.
Coggle requires JavaScript to display documents.
What is the most effective way to distribute the malaria vaccine? - Coggle…
What is the
most effective
way to
distribute
the
malaria vaccine
?
Effectivity
Reduction of deaths/mortality rate
Effect of age (factor)
Reducing no. infections
How to test for "effectivity"
Volunteers from outbreak region (different age group)
500 individuals
Low doses
Provided the different age groups with the low dosage of malaria vaccine
Over a certain time, test how many have
Infection rate
Identify trends (effectivness)
High doses
Vaccine
Type of vacccine
Toxoid
Inactivated
Messenger RNA
Live-attenuated
Protein Sub Unit
Success Rate
Efficacy of 77% in high doses
71% Efficacy in lowwer doses
Failures
Lack of deep understanding of malaria (how it works)
The disease is always changing
No discrete vaccine can be formed
Other new discoveries set back the work conducted on this vaccine
Malaria
Diseases
Biological understanding
Research that has already been conducted
Clinical testing regarding malaria
Possible Adaptations
The pathogen targets the younger populations
Pathogen
Parasite
Forms of transmission
Food Bourne
Water bourne
Close contact
Vectors
Mosquitos
Zoonotic
Number of infections
Mortality rate of malaria
4 times the mortality rate of covid
409,000 deaths in 2019
Distribution
Demographic
Age
Younger pop. (<16)
More succeptible to effects of malaria
Effectiveness of vaccine on younger generation
Older pop. (>50)
differences (older vs younger)
Volunteers
Clinical trials
Test overall effectiveness
Location
Population Density
Close contact
Effect on rate of transmission
Regions
Conducted in Burkina Faso
Outbreak locations
Data comparisons between locations
African continent
Landscape
Available resources
Lack of essential services
Access to specific technologies
Materials when conducting research