Please enable JavaScript.
Coggle requires JavaScript to display documents.
Diabetes + amputation - Coggle Diagram
Diabetes + amputation
-
Blood vessels vary in:
- length, diameter, wall thickness, tissue make-up
Atherosclerosis = hardening of the arteries Atherosclerosis is a disease in which plaque builds up inside your arteries.
- Chronic endothelial injury
- Endothelial dysfunction
- Smooth muscle emigration
- Macrophages/smooth muscle cells engulf lipids
- Smooth muscle cell proliferation and deposition of collagen
Arteriolosclerosis is a form of cardiovascular disease involving hardening and loss of elasticity of arterioles or small arteries and is most often associated with hypertension and diabetes mellitus
Atherosclerosis: The build-up of fats, cholesterol and other substances in and on the artery walls.
Amputation: partial/total removal of body part
- intentional surgery
- Severe trauma
- practised since 43,000 BC
- reasons: trauma, ritualistic, punitive, curative
- prostheses used for centuries
Why Amputate?
- control pain/diseases (peripheral vascular disease, malignancy, gangrene, severe trauma.
- punishment who committed a crime
- Revascularisation not possible
- Orthopaedic surgeons talk about the "three ds" = DANGER, DYING, DAMUSENSE?
- more common in lower extremity
-
Prostheses
- Soft-tissue envelope provides interface between remaining lower extremity & prosthesis (weight transfer)
- sufficient mass of muscle, full-thickness skin & subcutaneous tissue