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Hyaline degeneration - Coggle Diagram
Hyaline degeneration
Gross
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Tubular cells shows hyaline changes, giving glossy appearances
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Hyalinized tissue is tanslucent, firm and inelastic.
Microscopic
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Affected cells and tissue have lost their structural characteristic and have fused together into a homogenous mass. the fusing probably represents a process of coagulation and dehydration of the protein in the involved area. Since very few are present in the hyalinized mass, only a minimal amount of metabolic activity is taking place in the area.
Centrilobular hepatocytes have alterations in their cytoplasm characterized by increased eosinophilia with a fine to coarse flocculent texture.
Definition
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Term to describe a heterogenous group of tissue changes that have in common that they are translucent, homogenous and stain sharply with eosin.
Substances that have a homogenous glassy appearance in tissue sections are described as hyaline. Hyaline degeneration may occur in fibrous tissue in scars and some tumours due to the deposition of glycoproteins between collagen bundles. It may also occur in the walls of blood vessels.
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Etiology
No specific cause can be stated since it can be brought about by a variety of conditions which produces protein disturbances in the protein metabolism.
In some organs, the appearances of hyaline is normal alteration as is observed in the cornea of the eyes, stratum corneum of the skin, ovulation scars in the ovary.
