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REVERSIBLE & IRREVERSIBLE DISEASE - Coggle Diagram
REVERSIBLE & IRREVERSIBLE DISEASE
Restrictive: difficult to expand lungs, SOB, pulm. fibrosis ,sarcoidosis
Obstructive: difficult to exhale, SOB , Asthma & COPD
Microscopic
dilated congested capillaries
Oedema& eosinophilic infiltrate
protrudingthickening of basement membrane
hypertrophy of bronchial smooth muscle
desquamated bronchial mucosal cells
Hypertrophied mucous glands
occluding plugs
Failure to clear viscid tenacious of exudate
quality of exudate
Loss of ciliary action
excess & rapid exudate prod.
ASTHMA
Types
Extrinsic=good prognosis
hay fever & eczema
allergens>worsens attacks
childhood
Skin testing>>Wheal & Flare
Due to atopic hypersensitivity>IgE release>Type 1
Type 1Features
exposure to allergens
eosinophils present
Inhibited=Sodium Chromoglycate
TYPE 3
several hrs
Precipitins>fixation of complement>fever& leucocytosis
both delayed and immediate
responds to steroid therapy(ext. non atopic asthma)
Intrinsic
females predominate
no hypersensitivity
any age
prognosis not favourable
Define>>Irritability of tracheobronchial tree
Morphology(sputum)
Cruschmann;s spirals
Eosinophils mucus
desquamanted resp. epithelial cells
Charcot Leyden crystals
Postmortem
grey exudate
overinflated lungs>air trapped