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COPD - Coggle Diagram

- - - - Associated=chronic bronchiiitis
      - dead space
      - Anastomoses=pulm. HPT
    - - ↑ Resp. rate(comp. mechanism)
      - Pulm HPT less noticeable
  - - - homozygotes=liver disease(infancy)/lung disease(later)
      - proteolytic enzymes=destroy lungs>↓ alpha 1 antitrypsin(lung bases affected)
      - inherited deficiency of alpha 1 antitrypsin=plasma antiprotease
    - - cigarette=chronic bronchitis>damaged alveoli walls
      - Cadmium fumes>centriacinar emphysema>damage to lysosomes>enzyme release
- - - - Loss of cilia goblet cell metaplasia >↑ mucin
      - squamous metaplasia
    - - ↑ sputum viscosity
      - Serous secretions>normal antibacterial ,lysozyme,lactoferrin ,IgA , Airway specific protease inhibitor
      - ↑ mucous secretions(serous secretions)
      - ↑ sulphomucin>acidic 9dcrease neutral sialomucin)
      - enlarged