Transport across membrane

Selectively permeable

The cell membrane is describes as selectively permeable as only certain materials are transported between the cell and the extracellular space. Certain materials diffuse through the membrane more readily than others. The selective permeability is attributed to the lipid bilayer and to the presence of transport proteins that transport some materials across the membrane but not others.

Diffusion

The net movement of molecules or ions down a concentration gradient.

Particles move passively with energy input from a region of higher concentration to a region of lower concentration until the concentration gradient is zero.

The rate of diffusion is dependent on the concentration gradient, the thickness and surface area of the membrane and the solubility of the materials in the lipid bilayer

Osmosis

Osmosis is the passive diffusion of water across a selectively permeable membrane

Occurs from a region of higher water concentration to lower concentration

The movement of water is also affected by the solute concentrations in the extracellular environment.

The extracellular environment

Isotonic: Solute concentration outside the cell is equal to the solute concentration inside the cell.

Hypotonic: Solute concentration outside the cell is lower than the solute concentration inside the cell

Hypertonic: Solute concentration outside the cell is higher than the solute concentration inside the cell

Water diffuses passively from a region of lower solute concentration to a region of higher solute concentration

The cell volume increases when water diffuses into a cell from a hypotonic solution. Palisade mesophyll have a cell wall that maintains the cell structure as the volume increases, whereas red blood cells lack a cell wall and may burst when placed in a hypotonic solution. The cell volume decreases when water diffuses out of a cell and into a hypertonic solution. The decrease in volume of a palisade mesophyll cell and a red blood cell can inhibit life processes including metabolism, respiration and growth

Facilitated diffusion

passive movement of a solute down its concentration gradient and is facilitated by integral proteins in the membrane

Two types of transport protein: channel and carrier protein

Channel proteins

facilitate the diffusion of ions and other hydrophilic materials

Channel proteins have pores spanning the membrane which allows million of ions to diffuse across the membrane every second

Carrier proteins

Selectively bind to substrate in the cell or the extracellular environment

The shape or position of the carrier protein changes when the substrate bonds

The carrier protein releases the substrate to the opposite side of the membrane

The movement of water through the membrane is too slow so protein channel called aquaporins are used.

Active transport

Active transport uses carrier proteins to facilitate the movement of materials across the membrane in the opposite direction to the concentration gradient

Requires an input of ATP

Active process

Bulk Transport

Active transport of large molecules between the cell and the extracellular.

Two form: Endocytosis and Exocytosis

Endocytosis

bulk transport of material

To forms: phagocytosis and pinocytosis

Phagocytosis: transport of solid materials. In phagocytosis, the cell membrane produces two extensions called pseudopodia that surround the solid materials to be transported into the cell. The pseudopodia fuse and create a vesicle around the particle

Pinocytosis: transport of fluid. In pinocytosis, the cell membrane invaginates which allows the fluid to flow inwards. the liquid enclosed in vesicle

Exocytosis

bulk transport of materials from the cell to the extracellular environment

The contents of the vesicle are released into the extracellular environment as the vesicle fuses with the cell membrane

Surface Area to volume Ratio

Materials such as nutrients, waste products and gases are exchanged across the cell membrane and the rate of exchange is proportional to a cell's surface area while the amount of exchange is proportional to its volume.

Complex multicellular organisms such as animals and plants exhibit structure that increase the surface area to volume ratio for the exchange of materials. Such structure occur inside and outside the body of an organism

Cells with a greater surface area to volume ratio are more effective at sustaining metabolism as the rate of diffusion of raw and waste materials are equal to or greater than the rate of metabolism

Cells with a smaller surface area to volume ratio are unlikely to survive as they are unable to supply raw materials and remove waste materials at a rate that sustains metabolism. Therefore growing cells tend to divide when they reach a certain size to maintain a surface area to volume ratio that sustains the rate of metabolism