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PUBLIC HEALTH-RANDOMIZED CONTROL STUDIES - Coggle Diagram
PUBLIC HEALTH-RANDOMIZED CONTROL STUDIES
Researcher interventions>>influence outcome through exposure or treatment
PICO APPROACH
Analytic study
BIAS
Selection bias
Performance>when participants know the group they belong to
Attrition Bias>>participants who leave(loss to follow up)
Detection Bias
GOAL
difference in outcome>>attributed to exposure
2 equal groups
SELECTION BIAS
RANDOMIZATION-participants have equal chance of being treatment 0r control group
BLINDING>>hide allocation to participants-single vs double(both participants and researchers are blinded)
PERFORMANCE BIAS
Investigators might
treat the 2 groups differently
if they are not blinded
ATTRITION BIAS
withdrawals , protocol deviations
Loss to follow up
DETECTION BIAS
sujective-rely on paricipants
No blinding>>influence the measures
Objective detection of outcome
BLINDING
Types
Double-Investigators
Triple-Staticians
Single-participants
prevents systemic human error, crucial in subjective outcomes
Minimizes bias due to perceived treatment response, provider behavior, outcome assessment
Masking>drug(treatment) & placebo(control) same
Complex>>not always posssible