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MAINTENANCE OF ACID BASE BALANCE - Coggle Diagram
MAINTENANCE OF ACID BASE BALANCE
Define
Co-ordination of Respiratory and Renal Compensatory Mechanism
Balancing H+ losses and gains
RESPIRATORY COMPENSATORY
(quick)
Respiratory Acidosis:
Hypoventilation>↑pCO2>↓pH>
Resp. comp
:↑resp. rate(arterial & CSF chem. receptors stimulation) ,
renal. comp
:H+ secreted & HCO3- generated>↓pCO2 , ↓H+>↑HCO3-
change in
respiratory rate
>stabilize pH levels in ECF
Respiratory Alkalosis
:Hyperventilation>↓pCO2>↑pH>
Resp. comp
:↓resp. rate(arterial & CSF chem. receptors inhibited) ,
renal. comp
:H+ regenerated & HCO3- secreted>↑pCO2 , ↑H+>↓HCO3-
Affects Carbonic acid-bicarbonate Buffer system
RENAL COMPENSATORY
(hrs)
Metabolic acidosis
↑[H+]>↓pH>
Resp. Comp
:↑resp. rate(arterial & CSF chem. receptors stimulation) ,
renal. comp
:H+ secreted & HCO3- generated>↓pCO2 , ↓H+>↑HCO3-
Loss of HCO3-
>↓ bicarbonate reserve>↓pH(HCO3- can't accept H+)>↑resp. rate(arterial & CSF chem. receptors stimulation) ,
renal. comp
:H+ secreted & HCO3- generated>↓pCO2 , ↓H+>↑HCO3-
Metabolic Alkalosis
Resp. comp
:↓resp. rate(arterial & CSF chem. receptors stimulated) ,
renal. comp
*
:H+ regenerated & HCO3- secreted>↑pCO2 , ↑H+>↓HCO3-
Loss of H+>Gain of HCO3->↑pH
Change in
rates of H+ and HCO3– secretion or reabsorption
by kidneys
CLINICAL DISORDERS
Respiratory Alkalosis
: Panic Attack
Metabolic Acidosis:
diabetic ketoacidosis(↑acidic ketones)Chronic DiarrheaLactic acidosis/Chronic Renal failure
Respiratory Acidosis:
Emphysema/Pneumonia
Metabolic Alkalosis:
Severe Vomiting,