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psoriasis - Coggle Diagram
psoriasis
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definisi
golongan penyakit kulit dengan effloresensi : eritema, papula, skuama
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Faktor pencetus lainnya; infeksi,obat tertentu, stres, perubahan iklim, trauma
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predileksi
Plaque-type psoriasis is classically an extensor disease often involving the knees, elbows
gluteal cleft, lumbosacral region, and the umbilicus. Psoriasis may involve the scalp
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patofisiologi psoriasis
dysregulation of the cell-mediated, adaptive immune response
This dysregu- lation is likely triggered by hyperactivity of the innate immunological surveillance system to environmental antigens.
This overproduc- tion of Th1-related cytokines along with IL-12, -17, and -23 causes hyperproliferation of epidermal keratinocytes
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