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PHYSIOLOGY 2 - Coggle Diagram
PHYSIOLOGY 2
ELECTRICAL CONDUCTION
Rep. anion>into cell>
-ve charge
SA node>Atrial internodal fibres>AV node>Bundle of His>Purkinje fibres>Ventricular myocytes
Dep. : cation>into cells>
+ve cell charge
Cardiac AP>Flow of e- across ion channels in cardiac membranes>
E. activation of myocard. cells
Transmission of signals>Rhythmic Myocardial
contractions
Structures>
no generation contractile force
but electrical conduction & spontaneous dep.
EC -Coupling
(a) Action potential plateau phase
(b) Second messenger – Ca induced Ca release
(c)Sarcoplasmic reticulum Ca release
(d) Activation of troponin C – myofibril contraction , SERCA PUMP
Conduction Velocity
Depends on:
Amount of ions
going into cells
Interconnectedness
of Myocardial conduction cells
Purkinje-FASTEST>adequate blood ejection>contraction of myocytes
AV-SLOWEST>adequate time for ventricular filling
SA node
Determines normal(60-100bpm)
Not working>Latent Pacemaker cells
AV node: 40-60bpm
BoH:20-40 bpm
Purk. fibres:20-40 bpm
Primary Pacemaker>in the RA wall
Refractory Period
Absolute: No stimulus
Relative:Large stimulus>AP
No myocardial dep.
Excitatory Period
Myocard. cells>dep.
ATP Demand
Contraction
Relaxation
Excitation
ATP Supply
>>systole on L., Lil stores>O2 supply