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The role of kidney in hemeostatus - Coggle Diagram
The role of kidney in hemeostatus
Acid base Balance
Buffer System
70- 80 % reabsortion of HCO3
Kidneys have vital roleto re absorb and regenerate bicarbonate from the urine and to excrete hydrogen ions and fixed acids into urine.
exchange between K+ and H+ ions
Bicarbonate buffer system
Ammonia buffer system
Phosphate buffer system
Kidney's Role in Acidosis and Alkalosis
Acidosis: kidneys excretes more hydrogen ions and re-absorbs HCO3- into blood
Alkalosis: increases renal bicarbonate excretion resulting in loss of bicarbonate from the extracellular fluid and alkalization of the urine.
Fluid and Electrolyte regulation
maintain electrolytes concentration by regulating its concentration in the body
regulates Sodium, Potassium, phosphorous, Calcium and Magnesium through active and passive transports
regulate volume and composition of body fluids
Hormone Secretions
Renine that help synthesize angiotensin 2
Eriythropoietian, which stimulates the production of red blood cells in the bonemarrow
Calcitrol which Increases blood calcium level by increasing renal tubular re-absorption of calcium
Excretion Of metabolic Waste products and other toxic substances from body such as Urea, Creatinine and Bilirubin
Regulation of arterial
blood pressure
Renal Artery perfusion pressure directly regulate Sodium excretion (Pressure Natriuresis) and influences the activity of various vaso active systems
Link Title
The Kidney places a central role in the regulation of arterial blood pressure
Renin
Angiotensin Aldosteron System
Step 1: The Juxta Glomerular apparatus sense the
low pressure and release RENIN
RENIN Converts ANGIOTENSINOGEN to
ANGIOTENSIN 1
ANGIOTENSIN 1 travels through blood towards lungs
and converts ANGIOTENSIN 1 by ACE
ANGIOTENSIN 2 constricts: the efferent arteriole and cause decrease blood flow and results in increase hydrostatic pressure and thus the glomerular filtration increases
Aldosterone increases absorption of Sodium and water ,K+ excretion, increase fluid volume and increase BP
Step 2: ANGIOTENSIN 2 affects the adrenal glad
causes synthesis of ALDOSTERONE