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COHORT STUDIES, Glossary: Cohort>group of people who share similar…
COHORT STUDIES
Descriptive Cohort studies
Describes>>Frequency ,patterns & determinants of disease
No Comparison Group
Occurrence of disease in a group
e.g Birth Cohorts
Analytic Cohort Studies
AIM
Evaluate relationship btwn. exposure & outcome
FEATURES
Subdivide the group according to
exposure
Follow up
for a certain period of time>>dev. of new cases
Group of people
free of disease
@ the start of study
KEY FEATURE CONCIDERATIONS
@ Follow up
Complete
Follow up for all participants>>increase
validity
of results
30-40% Loss follow up>>doubts , bias
Appropriate follow up duration
If loss to follow up>>understand the differences btwn. lost to follow up and remaining groups
@ Baseline
Screen participants
Unexposed & exposed groups need to be similar in all factors except exposure
All participants free of disease
LIMITATIONS
Time consuming
Loss to follow up>
decrease validity
of results
Expensive
Risk of information
bias
inefficient for rare diseases
>require large sample size
STRENGTHS
Enable
calculation of incidence
>>measurement of
risk
Assess
if a single exposure has multiple outcomes
Determines
causal relationship
Efficiency>>for rare conditions
Glossary: Cohort>group of people who share similar characteristics