Malignant external infection is an infection that affects the external auditory canal and temporal bone.

When the infection reaches temporal bone through the fissure of Santorini,

Using the facial planes and venous sinuses, with the involvement of the skull base and the surrounding tissue leading to cranial nerve and intracranial structures invasion.

Containing the facial, glossopharyngeal, vagal, and accessory nerves.

The infection can spread, causing bony erosions and invasion of distant tissue.

Antpseudomonal betalactum antibiotics without aminoglycoside.