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HUNTINGTON'S DISEASE huntingtons-disease - Coggle Diagram
HUNTINGTON'S DISEASE
DEFINITION
An inherited condition in which nerve cells
in the brain break down over time
PATHOPHYSIOLOGY
The neuro-transmitters, gamma-aminobutyric and Ach are decreased.
Dopamine is not affected but the decrease of Ach cause
and putamen areas of the basal ganglia and extrapyramidal motor system.
relative increase of dopamine in the basal ganglia.
There is a destruction of cells in the caudate nucleus
The excess dopamine causes uncontrolled movements in Huntington's chorea.
PHARMACOLOGICAL MANAGENT
like Risperdal
Haloperidol
Antipsychotic medications
Thorazine
No treatment but assistance medication
CLINICAL MANIFESTATIONS
Delirium
Hallucination
Irritability
Anxiety
Fidgeting
Muscle spasms
Delusion
Difficulty speaking
Amnesia
Lack of concentration
Memory loss
NURSING CARE PLAN
Give medications as ordered
Advise patient to do regular exercises to reduce stiffness and tremors
Educate and support patient adjust to changes
Keep patient as close to uptight as possible when feeding
Prevent injury and possible skin breakdown by padding sides and head of the bed
CAUSES
Genetic mutations
