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IONIC MECHANISM IN ACTION POTENTIAL - Coggle Diagram
IONIC MECHANISM IN ACTION POTENTIAL
AT occur with help of carrier protein
UNIPORT
ANTIPORT
MECHANISM OF Active Transport
substance + CP = Sub-Pro Complex
SP moves inner membrane
substance released
ELECTROGENIC ACTIVITY of pump
Na/K pump moves 3 Na out 2 K in
1 pump= net loss of 1 +ve charge ion
continous activity cause REDUCTION in +ve charge ion inside cell
developing -ve potential inside
ELECTROGENIC ACTIVITY OF Na/K PUMP
Primary AT
Na/K transported Na/K pump
Na out & K inside membrane
HIGH intracellular K+ & low extracellular Na+ for cell survival
High K+ for glycolysis & protein biosynthesis
MECHANISM of Na/K Pump
3 Na ions attach inner receptor site CP
2 K+ outside receptor site CP
Na/K bind CP activate ATPase
ATPase break ATP to ADP
release of 1 high energy phosphate
ENERGY cause conformational change in CP
inner and outer surfaces change
dissociation and release of ions
CP of Na/K Pump
6 sites
3 receptor sites for Na
2 receptor sites for K
1 site for enzyme ATPase