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WOUND HEALING - Coggle Diagram

- - - - Contraction = Wound edges pull together to reduce defect.
      - Epithelialization =
        Epithelial cells spread to moist surface.
      - Granulation = Fibroblasts fill the defect and produces new capillaries.
  - - - Hemostasis = Vasoconstriction to stop bleeding. Accomplish by platelet aggregation & thromboplastin clot.
      - Inflammation = Vasodilation initiated by histamine, followed by phagocytosis of pathogens by the macrophages.
- - - - Surgically incised.
      - Without much loss of cells and tissues.
      - Clean and uninfected.
      - Edges of wound are approximated by surgical sutures.
    - - Acute inflammatory response.
      - Epithelial changes.
      - Initial haemorrhage.
      - Organization.
  - - - Having extensive loss of cells and tissues.
      - The wound is not approximated by surgical sutures but is left open.
      - Open with a large tissue defects, at times infected.
    - - Epithelial changes.
      - Granulation tissue.
      - Inflammatory phase.
      - Wound contraction.
      - Initial haemorrhage.
      - Presence of infection.