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OSTEPOROSIS DRUGS - Coggle Diagram
OSTEPOROSIS DRUGS
mechanism of action
due to acidic environment generated by osteoclasts
thet become cinsumed through endocytosis
these drugs are released to bone surface
this induce osteoclast apoptosis
biphosphonates are common anti-osteoporosis drugs with anti-resorptive function
indications
hypocalcaemia of malignancy
paget disease
osteoporosis
malignances
abnormal uterine bleeding
side effects
gastric ulcers
difficulty in swallowing
nausea
tiredness
bone pain
contra-indications
oesophagal abnormalities
diseases slowing down gastric emptying
oesophagitis
storage
at room temperature
away from sunlight
cool and dry place
names
boniva
actonel
fosmax
references
www.nchi.nih.gov
www.webmb.com
examples
alendronate
route
oral and IMI