Please enable JavaScript.
Coggle requires JavaScript to display documents.
Fluvastatin - Coggle Diagram
Fluvastatin
Side effects
Stomach upset or pain
Indigestion
Muscle pain
Headache
Diarrhoea
Insomnia
Confusion
Fatigue
Skin problems
Mechanisms of action
Inhibits enzyme HMG-CoA reductase
HMG-CoA reductase is responsible for converting HMG-COA to mevalonate
The rate limiting step in cholesterol biosynthesis
Inhibition results in a decrease in hepatic cholesterol levels
Which stimulates the synthesis of LDL Receptors
Increases hepatic Uptake of LDL cholesterol
The end result is decreased levels of plasma total and LDL cholesterol.
Indications
Hypercholesterolemia
High amount of total blood cholesterol
Prevention of coronary heart disease
Reduce low density lipoprotein cholesterol
Contraindications
Hypersensitivity to drug
Liver disease
Pregnancy
Breastfeeding
Storage
Cool dry place/room temperature
Away from light
Keep out of reach of children
Name
Lescol
Route of administration
Orally