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MALE AND FEMALE HORMONAL DRUGS, REFERENCES - Coggle Diagram
MALE AND FEMALE HORMONAL DRUGS
ESTRADIOL
CONTRA INDICATIONS
Do not use drug when you were pregnant
Smoking can increase risk of blood clots,stroke, heart attack
caused by birth control pills specially in f you are older than 35.
SIDE EFFECTS
heavy feeling
chest pains
Imbalance
nausea
dark urine
sweating
confusion
ROUTE OF ADMINISTRATION
orally
STORAGE CONDITIONS
store between 15 to 30 degrees celsius
CONTRA INDICATIONS
undiagnosed vaginal bleeding
liver disease
angioedema or anaphylactic reaction
deep venous thrombosis
blood clots
pulmonary embolism
MECHANISM OF ACTION
acts as a growth hormone for tissue of the reproductive organs, supporting the lining of the vagina, the cervical glands, the endometrium, and the lining of the fallopian tubes. It enhances growth of the myometrium
INDICATIONS
Reduce pain associated with monopause
Regulate ovulation
Reduce hot flushes
Reduce dryness
maintain reproductive system
DANAZOL
MECHANISM OF ACTION
growth and development of male sex organs
maintanance of secondary male sex
increase the retention of nitrogen
increase protein anabolism and decrease protein catabolism
increase the production of red blood cell
CONTRA INDICATIONS
allergy
pregnancy
liver dysfunctions
cv disease
presence of prostate
ROUTE OF ADMINISTRATION
buccal, IMI, dermal
INDICATIONS
treat endometriosis
treat fibrocystic breast disease
it leads to a drop in FSH
treat hereditary angioedema
SIDE EFFECTS
acne
edema
deepening of voice
oily skin or hair
weight gain
sweating
fatigue
rash
STORAGE CONDITIONS
store in room temp
away from sunlight
make sure the ampulle is not broken
OXANDRIN
SIDE EFFECTS
vilirization
gynecomastia
testicular atropy
baldness
change in libido
hoarseness
deepening
clitoral enlargement
INDICATIONS
anemia
angioedema
promote weight gain
enhance athletic perfomance
MECHANISM OF ACTION
promote body tissue building
reverse catabolic destroying process
ROUTE OF ADMINISTRATION
ORAL
CONTRA INDICATIONS
allergy
pregnancy
lactation
liver dysfunction
prosstate cancer
Coronary disease
breast cancer
STORAGE CONDITIONS
Store at room temperature away from sunlight.
protect from sunlight ang moisture.
store in a cool dry place.
NEFARELIN
MECHANISM OF ACTION
Is the desensitization of pituitary GnRH receptors leading to a decrease in gonadotropin release and ovarian hormone serum concentration.
STORAGE CONDITIONS
stored at room temperature between 15 to 30 degrees celsius
ROUTE OF ADMINISTRATION
Subcutaneous
nasal
SIDE EFFECTS
Increase in pubic hair growth.
Decreased sexual interest or changes in sexual desire.
Vaginal dryness.
Muscle pain.
INDICATIONS
endometriosis
CONTRA INDICATIONS
A mother who is producing milk and breastfeeding.
Increased cardiovascular event risk.
Pregnancy.
A patients with gonadotropin-releasing hormone (GnRH) analogs
hypersensitivity.
CYCLOFENIN
MECHANISM OF ACTION
It relieves smooth muscle spasm of the gastrointestinal tract.
CONTRA INDICATIONS
Severe ulceration of the colon
liver disease
Kidney disorder
Urinary tract disorders
Gastric inflammation
INDICATIONS
Gastro-intestinal distress due to spasm.
Painful menstruation Smooth muscle spasm.
STORAGE OF CONDITIONS
Stored between 20 to 25 degrees celsius
SIDE EFFECTS
Loss of appetite
Dry mouth
Dizziness
ROUTE OF ADMINISTRATION
IMI
sublingual
inhalation
oral
PREGNYL
CONTRA INDICATIONS
In patients with prior allergic reaction to human chorionic
gonadotropin.
SIDE EFFECTS
Depression
Precocious puberty.
Restlessness
Gynecomastia
CONDITIONS
Prepubertal cryptorchidism not due to anatomical obstruction.
Selected cases of hypogonadotropic hypogonadism in males.
Induction of ovulation and pregnancy in the anovulatory, infertile, woman in whom the cause of anovulation is secondary and not due to primary ovarian failure, and who has been appropriately
pretreated with human menotropins.
STORAGE CONDITIONS
15 to 30 degrees celsius
Reconstituted solution is stable for 60 days when refrigerated.
ROUTE OF ADMINISTRATION
Intramuscular only
MECHANISM OF ACTION
Pregnyl vial depends upon the purpose for which it is being used, the sex of the patient, and the level of maturity of the patient to
whom it is administered.
REFERENCES
Lewis, S.L., Dirksen, S.R., Heitkemper, M.M., Bucher, L., 2011.Medical-Surgical Nursing; Assessment and manangement of clinical problems.9nth Ed.Canada.Elsevier Mosby.
Hinkle, J.L., Cheever, H.K., 2010.Brunner and Suddarth’s textbook of medical surgical nursing.12th edition.Philadelphia.Wolters Kluwer.
Greenstein, B., 2008. Trounce’s clinical pharmacology for nurses. Eighteenth edition. Elsevier Health Sciences.