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ANTIGOUT DRUGS - Coggle Diagram
ANTIGOUT DRUGS
Probenecid
mechanism of action
stops the excretion of renal
blocks reuptake
prevents renal tubular transporter
aids in excretion of uric acid that result from illnesses.
indications
To treat gout
raise the excretion of uric acid
treat hyperuricemia
nursing consideration
side effects
nausea
loss of food interest
dizziness
cramps
stomach ache
regular urge to urinate
storage
store at room temperature
away from light
contraindications
kidney disease
renal impairement
deficiency of red blood cells
stomach ulcer
route of administration
to be administered by mouth
sulfinpyrazone
mechanism of action
prohibit multidrug resistance protein
aids in urinary excretion of uric acid
prohibit simultaneously administration of citrate
prohibits reabsorption of uric acid
indications
lessen platelets aggregation
treat gout
lessen the release of ADP
nursing consideration
contraindications
in pregnancy
in ulcer of mucous membrane
renal impairment
kidney stones
side effects
rash
nausea
heart burn
pain in the abdomen
vomiting
storage conditions
away from direct sunlight
away from moist places
at room temperature of 15-30 degrees celcius
route of administration
by mouth
allopurinol
mechanism of action
inhibit uric acid manufacturing
prohibit purine synthesis
inhibit enzyme xanthine oxidase
indications
lessen high levels of uric acid in the blood
prevent gout
several types of kidney stones
nursing consideration
contraindications
allergies
chronic heart failure
liver issues
severe dehydration
side effects
vomiting
diarrhea
headache
drowsiness
muscle ache
route of administration
orally
storage conditions
away from sunlight
away from direct heat
colchine
mechanism of action
prevent cancer cells from migrating
bind to tubulins
prohibit inflammatory cells in gout tissue
inhibit phagocytosis of uric acid
indications
aids in abdomen pain
treat gout episodes
prevent pericarditis
nursing consideration
side effects
body pain
diarrhea
muscle ache
fever
vomiting
contraindications
dialysis
renal disease
renal failure
renal impairment
route of administrations
taken orally
by injection
storage conditions
away from light
at room temperature
References
Gout. Centers for Disease Control and Prevention.
https://www.cdc.gov/arthritis/basics/gout.html
. Accessed Dec. 23, 2020.
Caffo AL. Clinical manifestations and diagnosis of gout.
https://www.uptodate.com/contents/search
. Accessed Dec. 23, 2021.
