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Potassium-Sparing Diuretics(triamterene)
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Potassium-Sparing Diuretics(triamterene)
Mechanism of action
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it inhibits the reabsorption of sodium ions in exchange for potassium and hydrogen ions at that segment of the distal tubule under the control of adrenal mineralocorticoids (especially aldosterone)
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Side effects
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hyperkalemia, hypokalemia
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weakness, fatigue, dizziness, headache, dry mouth
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Nurses consideration
Assess for the mentioned cautions and contraindications (e.g. drug allergies, fluid and electrolyte disturbances, hepatorenal diseases, glucose tolerance abnormalities, etc.) to prevent any untoward complications
Inspect skin (note presence of edema and status of skin turgor) to determine hydration status and have a baseline data for effectiveness of drug therapy
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References
Seaman J, Landry JT (2011). Mylan 50 Years of Unconventional Success. University Press of New England. p. 50. ISBN 9781611682700.
FDA Approval History NDA 019129: Maxzide Page accessed Sept 8, 2016
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