Please enable JavaScript.
Coggle requires JavaScript to display documents.
Jaundice - Coggle Diagram
Jaundice
(exclusively) bilirubin ↑
indirect hyperbilirubinemia
direct < 15%
inherited disorder
Gilbert's syndrome
Crigler-Najjar syndrome
type I
type II
drug
rifampicin
probenecid
overproduction of heme
hemolytic disorder
inefficient erythropoiesis
direct hyperbilirubinemia
direct > 15%
inherited disorder
Dubin-Johnson syndrome
mutation in MRP2
Rotor syndrome
deficiency of hepatic drug reuptake transporters OATP1B1 & OATP1B3
bilirubin ↑ & other liver tests ↑
hepatocellular
ALT, AST ↑ >> ALP ↑
acute
ALT ↑ >> AST ↑
acute viral hepatitis
hepatitis D
hepatitis E
hepatitis C
hepatitis B
hepatitis A
nonalcoholic steatohepatitis (NASH)
chronic
ALT ↑ << AST ↑
chronic viral hepatitis
hepatitis B
hepatitis C
alcoholic hepatitis
cholestatic
ALT, AST ↑ << ALP ↑
obstructive jaundice
symptom
hyperbilirubinemia
prolonged prothrombin time
classification
bile duct dilation
choledocholithiasis
symptom
biliogenic pancreatitis
3 more items...
painless
cholangiocarcinoma
risk factor
primary sclerosis cholangitis (PSC)
ulcerative colitis (UC)
hepatitis B
hepatitis C
diagnosis
echo
1 more item...
pancreatic periampullary tumor
cholecystitis
primary biliary cholangitis (PBC)
primary sclerosis cholangitis (PSC)