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Chronic canine hepatitis, COST --> long term tx can be expensive, esp…
Chronic canine hepatitis
signalment
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female dobermann pinschers, golden retrievers
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also bedlington terrier, labrador retriever, skye terrier, west highland white terrier, standard poodle
pathophysiology
aeitology
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immune mechanisms and copper accumulation may play roles anti-epileptics and leptospirosis are also implicated
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diagnosis
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client hx
vague hx of anorexia, lethargy, depression, wt loss
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Haematology
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microcytic, hypochromic anaemia consistent with a chronic GI bleed 2ry to portal hypertension and intestinal oedema
histopathology
liver biopsy (take 3 biopsies when using percutaneous method, may miss lesions if only 1 biopsy is taken)
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treatment
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control coagulopathy and anaemia (vitamin K, 2mg/kg q12h IM or SC)
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standard tx
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diet low Cu content, Zn and antioxidants added
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gastric acid reducers, gastric ulcer medications
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imaging can reveal small, bright irregular liver with evidence of portal hypertension or acquired shunts and ascites
COST --> long term tx can be expensive, esp if using ursodeoxycholic acid. Low-moderate expenses incurred in establish dx
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