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ACROMEGALY - Coggle Diagram
ACROMEGALY
clinical manifestations
enlarged jaw and tongue
prominent brow
swollen and painful joints
thickened skin
hoarse, deep voice
splayed fingers and toes
Diagnostic studies
MRI scan
head CT scan
Blood tests to measure IGF-1
complete eye examintion
Treatment
radiation therapy
drug therapy with cabergoline and octreotide and pegvisomant
hypophysectomy
periodic evaluation
nursing intervention
relieve pressure around any growing pirtuitary tumors
maintain normal pirtuitary function
bring GH production levels to normal
treat any hormone deficiences
causes
pirtuitary adenoma
mutation in guanine nucleotide
benign tumor
pathophysiology
hypersecretion of GH from somatotroph cells
benign growth hormone secreting adenoma
references
https://www.ncbi.nlm.nih.gov/books/NBK538261/
Melmed S. Acromegaly. N Engl J Med 1990;322:966
rare condition characterized by excessive bone and soft tissue due to overproduction of GH