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Route of drugs administration - Coggle Diagram
Route of drugs administration
defination
It is the path by which a drug, fluid, poison or other substance is taken into the body. It is classified by the location at which substance is applied.
various routes of drug administration
Oral
sublingual
Rectal
parenteral (intravenous, intramuscular and subcutaneous
Topical
Factors that affect absorption and distribution of drugs in the body
Route of administration
[ IV meds absorb faster than PO meds]
Blood flow & supply
Pain and Stress
GI mortality
Exercise
Food or other drugs
PH
Consequences of metabolism and excretion on drug efficacy & duration
Enzimitically mediate alterations of. Drug structure
Metabolism of a drug decreases its therapeutic effect
It decreases the duration and intensity of drug action
Majority drugs are metabolized to increase their water solubility to allow elimination
Genetical variations in drug response
Toxic metabolites