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IMMUNE RESPONSE - Coggle Diagram
IMMUNE RESPONSE
Antigen enters the body
Activation of the innate immune system
First line of defense
Skin
Mucous membranes
Antimicrobial peptides
Second line of defense
Blood
Phagocytosis
Nonphagocytic killing
Pathogen bypass of the innate system
Activation of the adaptive immune sytem
Recognition of antigens from immune receptors
Endogenous antigen processing
Proteases cut sections of polypeptide within the cell to receive epitopes
Moves to the ER and then binds with the MHC I in order to allow for the combination to be detected within the cell by immune cells.
Exogenous antigen processing
Dendrites phagocytizes pathogen cell
Cell is cut into segments using a phagolysosome to obtain epitopes as well
MHC II fuses with phagolysosomes that contain epitopes leaving complexes on the cells surface
Cell interactions
If it is an infected host cell, it will go through apoptosis via phagocytosis or destruction by T-cells
Can signal the immune system to respond to a foreign pathogen that has entered the body and has gone past the innate system
Release and use of cytokines
Cytokines are regulatory proteins used as signals in order to tell the immune system that there is an unknown pathogen in the body
Memory B cells
create plasma cells to help create a antibody load in order to fight a known pathogen
Memory T Cells
Create cytotoxic T cells for future destruction of infected cells or pathogens.