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Immunosuppressant drugs - Coggle Diagram
Immunosuppressant drugs
calcineurin inhibitor
ciclosporin
indication
kidney, liver, heart transplant rejection
nursing consideration
side effect
nausea, vomiting, diarrhoea
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unusual hair growth, headache
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mechanism of action
calcineurin activates transcription of interleukin 2, ciclosporin binds with cytosolic cyclophilin to form a complex which inhibits calceneurin