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Cholinergic drugs or Stimulants - Coggle Diagram
Cholinergic drugs or Stimulants
Anticholonesterase
Side effects
nausea
vomiting
headache
insomnia
Storage Conditions
store under the temperature of 5- 28 degrees Celsius
Contraindications
hypersensitive to the drug
Indications
Alzheimer disease
certain types of poisoning
urinary incontinence
overactive bladder
Route of Administration
Oral
injection route
Mechanism of action
any of several drugs that prevent destruction of the neurotransmitter acetylcholine by the enzyme acetylcholinesterase within the nervous system
Acetylcholine acts to transmit nerve impulses within the parasympathetic nervous system
Neostigmine
Contraindications
hypersensitive to the drug
urine irritability
not used in pregnant women
Side Effects
salivation and fasciculation are the most common. Bowel cramps and diarrhea may also occur.
Indication
indicated for the symptomatic treatment of myasthenia gravis.
used in difficulty in breathing
And in prolong therapy
Storage Conditions
store in 15- 30 degrees Celsius
protect from light
Mechanism of action
prevent the parasympathetic effects that are enhanced when acetylcholine acts on muscarinic receptors.
Route of Administration
administered in oral route
Pyridostigmine
Contraindications
contraindicated in cases of mechanical intestinal or urinary obstruction and should be used with caution in patients with bronchial asthma
Side effects
Common side effects include nausea, diarrhea, frequent urination, and abdominal pain.
More severe side effects include low blood pressure, weakness, and allergic reactions
Indication
medication used to treat myasthenia gravis.
It is also used together with atropine to end the effects of neuromuscular blocking medication of the non-depolarizing type
Storage condition
keep this drug in fridge
between temperature of 15-30 degrees Celsius
Mechanism of action
inhibits acetylcholinesterase in the synaptic cleft, thus slowing down the hydrolysis of acetylcholine
Route of Administration
This drugs can be given via oral and injection route
Muscarine
Contraindications
not given to person who do hypersensitive to the drug
Asthma or Chronic Obstructive Pulmonary Disease (COPD)
Peptic Ulcer
Coronary Vascular Disease
Side effects
vomiting
Diarrhea
Urination
Bradycardia
Lacrimation
Indication
Muscarinic receptors are primarily on the postsynaptic cell membrane of smooth muscle, cardiac muscle, and exocrine gland cells
Storage Conditions
protect from light
Mechanism of action
acts in the peripheral nervous system, where it competes with acetylcholine at its receptor binding sites
Route of Administration
administered in oral route