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VIROPTIC IMG_20210410_012647_413 - Coggle Diagram
VIROPTIC
Indications
Treatment of recurrent epithelial keratitis due to herpes simplex virus types 1 and 2
Treatment of primary keratoconjunctivitis
contraindications
hypersensitivity reactions
chemical intolerance to trifluridine
Side effects
superficial punctate keratopathy
epithelial keratopathy
Mild, transient burning or stinging upon instillation and palpebral edema
hypersensitivity reaction
stromal edema
increased intraocular
hyperemia
Storage
refrigerate at 2 degrees to 8 degrees Celsius
Route of administration
Ophthalmic route (eye drops)
Mechanism of action
irreversibly inhibits thymidylate synthetase
triphosphate competitively inhibits DNA polymerases
Inhibition of viral DNA synthesis
