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LEFLUNOMIDE IMG-20210411-WA0025 - Coggle Diagram
LEFLUNOMIDE
Mechanism of action
Which plays a key role in the de novo synhesis of uridine monophosphate
Which is required for the synthesis of DNA and RNA
The mitochondrial enzyme dihydroorotate dehydrogenase
Is an immunomodulatory drug that achieves its effects by inhibiting
Indications
Rheumatoid arthritis
Psoriatic arthritis
Contraindications
Patient with severe hepatic impairment
Leflunomide hypersensitivity
Previous or current skin reaction
Side effects
Chest pain
Fast/pounding heartbeat
Cough
Vision changes
Mental/mood changes
Increased thirst/urination
Route
Orally
Storage
Controlled room temperature of 25 degrees celcius
