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antiobesity drugs - Coggle Diagram
antiobesity drugs
name
lipase inhibitor (orlistat)
contraindications
gallbladder desease
hypothyroidism
malabsorption syndromes
organic causes of obesity
contraindications include hypersensitivity to orlista
mechanism of action
Their mode of action is to inhibit gastric and pancreatic lipases
enzymes that play an important role in the digestion of dietary fat
Lipase inhibitors belong to a drug class that is used as an antiobesity agent
Lipase inhibitors are classified in the ATC-classification system as A08AB (peripherally acting antiobesity products).
side effects
fecal incontinence
flatus with discharge and abdominal cramping
oily spotting
a raised blood pressure
indications
Orlistat is used to aid in weight loss, or to help reduce the risk of regaining weight already lost
This medicine must be used together with a reduced-calorie diet and increased physical activity
Orlistat blocks some of the fat that you eat, keeping it from being absorbed by your body
storage condition
Keep the bottle tightly closed
Throw away any unused orlistat after the expiration date on the medicine label has passed
Store at room temperature away from moisture, heat, and light
route of administration
120 mg orally three times a day with each main meal containing fat. The dose may be taken during the meal or within 1 hour of completing the meal.
name
centrally acting drug (phentermine)
mechanism of action
stimulating it to secrete the neurotransmitter
called norepinephrine that helps to regulate appetite.
Phentermine Mechanism of ActionPhentermine acts on the hypothalamus area of the brain
indications
Phentermine is used together with diet and exercise to treat obesity
especially in people with risk factors such as high blood pressure
which increases your heart rate and blood pressure and decreases your appetite
high cholesterol, or diabetes.
It stimulates the central nervous system (nerves and brain)
contraindications
Psychiatric conditions that may be associated with agitated states include but are not limited to anxiety disorders, schizophrenia, psychosis, and mania
Monitor patients closely for changes in moods and behaviors.
Phentermine is contraindicated in patients with agitated states
side effects
dry mouth
insomnia
increased heart rate
dizziness
storage conditions
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light
keep from freezing
route of administration
phentermine hydrochloride 15 mg or more per oral capsule or tablet
15 to 37.5 mg PO once per day as a single dose every morning before breakfast or approximately 2 hours after breakfast.