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Reproductive drugs - Coggle Diagram
Reproductive drugs
fluoxymesterone
route of admnistration
orally
storage conditions
15-30 degrees C away from light and moisture
indications
replacement therapy for deficiency of endogenous testosterone
contra-indications
renal disease
breast cancer
hyperthyrodism
hypercalcemia
mechanism of action
produces retention of nitrogen, sodium and phosphorus
increses protein anabolism
decreases amino catabolism
side effects
hair loss
skin colour changes
methyltesterone
storage conditions
25 degrees C away from light and moisture
route of admnistration
P.O
buccal admn.
side effects
baldness
headache
Hair loss
increased or decreased sexual activity
contra-indications
prostatic hypertrophy
breast cancer
myocardial infraction
geriatric
indication
delayed puberty in males
androgen replacement therapy related to cryptorchirdism
erectile dysfunction
mechanism of action
binds to cytosolic androgen receptors
danazol
side effects
dark coloured urine
increased oiliness of skin
acne
swelling of the feet
indications
Hypogonadism in males
contra-indication
high cholesterol and high triglycerides
chronic heart failure
liver problems
storage conditions
room temperature 15-25 degrees C
mechanism of action
inhibits gonotrophic secretion and decrease testoterone level
route of admnistration
P.O
testosterone
storage conditions
20-25 degrees C away from light
mechanism of action
activation of the androgene receptor AR (directly or as DHT)
contraindications
prostate gland cancer
diabetese
overweight
polycythemia vera
indications
muscle wasting
primary and secondary hypogonadism
route of administration
IMI
side effects
pain and swelling at site
breast swelling
tingly feeling
headache