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Otic drugs Screenshot (109) - Coggle Diagram
Otic drugs 
name: ofloxacin
mechanism of action-inhibition topoisomerase (DNA gyrase), enzymes, which inhibit relaxation of supercoiled DNA and promote breaking of double stranded DNA.
contra-indication- tablets are contra indicated in person with hypersensitivity associated with the use of oflaxacin.
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storage condition- store the medicines in a closed container at a room temperature, away from heat, moisture and direct light.
side effects- nausea, vomiting, diarrhea, headache, dizziness, skin itching.
route of administration- oral, intravenous, opthalmic / otic (eye drops and ear drops)
name: sinuend
contraindication-severe liver or kidney function impairment, cardiovascular disease, kidney disease, hypertension.
mechanism of action- they have analgesics, antipyretic, sympathomimetic and histamine.
storage condition- store below 25 degrees celcius, protection from light and moisture.
side effect increase risk of arrhymias, vomiting may occur, insomia.
route of administration- orally, topica;.
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name: promaxine
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side effect- redness, irritation, swelling, burning, stinging or pain at affected area and also dryness at affected area.
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storage condition- store at room temperature, away from heat.
name: azithromycin
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indications- indicated to treat lower respiratory tract infection, upper respiratory tract.
side effects- neutropenia, palpation, chest pains, nausea, anorexia.
mechanism of action- azithromycin is absorbed rapidly from the gastrointestinal tract with an oral bioavailability of approximately 37% peak concentration occur approximately 2-3 hours after oral administration.
name: acetic acid
side effects- severe burning or irritation after using the ear drops, mild stinging or burning after use, difficult in breathing, swelling of lips.
indication- used to treat outer ear infection and also treating the infection reduces pain and swelling in the ear.
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mechanism of action- it is effective against microorganisms in patients with acute diffuse external otitis.
name: benzocaine
contraindication- contraindicated to abnormal heart rhythm decreased lung function, seizures, metheglobinemia, anemia from pyruvate kinase and glucose-6-phosphate dehydrogenase deficiency.
storage condition- store in a closed container at room temperature, away from heat, moisture, and direct light.
mechanisms of action- reversibly stabilizes the neuronal membrane which decreased its permeability to sodium ions and also inhibits thereby blocking the initiation and conduction of nerve impulse.
indication- it is indicated to treat a variety of pain. it maybe used for local anesthesis of oral and pharyngeal mucous membrane and otic pain.
side effect- headache, weakness, dizziness, breathing problem, fast fear rate, bluish colored skin, swelling, warmth or redness.
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name; clotrimazole
indication- effective treatment for mouth candidiasis, pharynx for dermatophutoses and other superficial fungal skin infection.
mechanism of action- it works kill individual candida of fungal cell walls, it binds to phospholipids in the cell membranes and inhibit biosynthesis of steroids and other steriods required for cell production.
side effects- redness, blistering, stinging, swelling.
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contraindication- it is contra-indicated in patients with oncymosis, pregnancy,breastfeeding.
name: ciprofloxacin
routes of administration- by mouth, intravenous, topical (ear drops, eye drops)
side effects- itching or pain after using the drops, fussiness or irritability, headache, stuffy nose nd sore throat.
indications- indicated for the treatment of infections caused by susceptible isolates of the designated microorganisms of the acute otitis media and acute otitis externa
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contraindication- the following are contraindicated with this drug; lower seizures threshold, low amount of magnesium in the blood, low amount of potassium in the blood.