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Propylthiouracil propycil-propylthiouracil- - Coggle Diagram
Propylthiouracil
Side effects
Mild rash
Headache
Vomiting
Nausea
Dizziness
Joints and muscles pain
Liver damage
Indications
Also used to treat multinodular goiter
Used as a treatment of hypothyroidism which is due to Graves' disease
Contraindications
Not to be used in persons with hypothyroidism
In people with known hypersensitivity
And liver diseases
Storage
Route of administration
Administered orally
Mechanism of action
And act by inhibiting the enzyme thyroid peroxidase
Which usually functions to convert iodide to iodine molecule
It works by inhibiting the production of a new thyroid hormone in a thyroid gland
And incorporate the iodine molecule into amino acid thyrosine.
