CENTRAL NERVOUS SYSTEM STIMULANTS - Coggle Diagram
CENTRAL NERVOUS SYSTEM STIMULANTS
SIDE EFFECTS: dizziness, dry mouth, difficulty sleeping (insomnia), irritability, nausea
STORAGE CONDITION; Store phentermine at room temperature. Keep it at a temperature between 68°F and 77°F (20°C and 25°C). Keep this drug away from light.
CONTRA-INDITION: overactive thyroid gland. diabetes. psychotic disorder drug abuse. glaucoma, an increased pressure in the eye. high blood pressure.
INDICATION; Phendimetrazine is similar to an amphetamine. Phendimetrazine stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite. Phendimetrazine is used together with diet and exercise to treat obesity.
ROUTE OF ADMINISTRATION: Oral
MACHANISM OF ACTION; A phenylalkylamine sympathomimetic with activity similar to amphetamines that stimulates the central nervous system (CNS) and elevates blood pressure (BP) most likely mediated via norepinephrine and dopamine metabolism. Causes stimulation of the hypothalamus.
CONTRA-INDICATIONS: Contraindications for amphetamines include: sensitivity to amphetamines or their derivatives. cardiovascular disease or arteriosclerosis, a thickening or hardening of artery walls. moderate to severe hypertension, or high blood pressure
SIDE EFFECTS: headache. upset stomach. trouble sleeping. decreased appetite. unpleasant taste in your mouth. nervousness. dizziness. sexual dysfunction.
INDICATION: Amphetamine is FDA-approved for the treatment of attention-deficit/hyperactivity disorder (ADHD) and narcolepsy. It has indications as a first-line agent for ADHD in adults and children six years of age and older. Amphetamine is also a second-line agent for the treatment of narcolepsy
MACHANISM OF ACTION: Amphetamine increases monoamine and excitatory neurotransmission in the brain, with its most pronounced effects targeting the norepinephrine and dopamine neurotransmitter systems.
STORAGE CONDITIONS: initial temperature of 100 °C held during 5 min, 40 °C/min to 220 °C of final temperature
ROUTE OF ADMINISTRATION: Its can be oral and intramuscular
CONTRA-INDICATION: manic behavior. psychotic disorder. suicidal thoughts. depression. high blood pressure. mitral valve prolapse syndrome. left ventricular hypertrophy.
SIDE EFFECTS; Headache. Nausea. Dry mouth. Dizziness. Anxiety. Diarrhea. Difficulty sleeping (insomnia)
INDICATION: is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep apnea (OSA), narcolepsy, or shift work disorder (SWD). In OSA, NUVIGIL is indicated to treat excessive sleepiness and not as treatment for the underlying obstruction.
STORAGE CONDITION: Store at room temperature away from moisture and heat
MACHANISM OF ACTION: Although the exact mechanism of action has yet to be fully elucidated, armodafinil appears to inhibit the reuptake of dopamine by binding to the dopamine-reuptake pump, which leads to an increase in extracellular dopamine levels in some brain regions
ROUTE OF ADMINISTRATION: Oral
CONTRA-INDICATION: Contraindications to atomoxetine include allergy to atomoxetine, use of an MAOI within the last 14 days, narrow-angle glaucoma, history of pheochromocytoma, and cardiac disorders which cannot tolerate increases in blood pressure or heart rate
SIDE EFFECTS: heartburn. nausea. vomiting. loss of appetite. weight loss. constipation
INDICATION: Atomoxetine is indicated for the treatment of attention deficit hyperactivity disorder (ADHD) in adults and children over the age of 6. Although atomoxetine is only FDA approved for the treatment of ADHD, it is sometimes used off-label for the treatment of adult patients with treatment-resistant depression
STORAGE CONDITION: Store in a cool, dry place, away from direct heat and light
MACHANISM OF ACTION: The mechanism of action of atomoxetine is unclear, but is thought to be related to its selective inhibition of presynaptic norepinephrine reuptake in the prefrontal cortex. Atomoxetine has a high affinity and selectivity for norepinephrine transporters, but little or no affinity for various neurotransmitter receptors.
ROUTE OF ADMINISTRATION: capsules are intended for oral administration only