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PICROTOXIN picrotoxin19462 - Coggle Diagram
PICROTOXIN
SIDE EFFECTS
Delirium
Gastro-enteritis
Convulsions
Unconsciousness
INDICATIONS
Antidote in poisoning by CNS depressants
ROUTE OF ADMINISTRATION
Subcutaneously
Intravenously
STORAGE CONDITIONS
15°C to 30°C
Do not freeze
MECHANISM OF ACTION
inhibitor for GABA receptors
In high concentrations it reduce amplitude of GABA currents.
Acts as non-compititive antagonist
Have antagonist effect as they block the inhibitory action of
and also cause convulsions
of GABA receptors thus mimics epilepsy
CONTRAINDICATIONS
Tachyarrhythymias
Ventricular arrhythmias
Heart block
Should not be used by people with tachycardia,