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BRUGIA MALAYI - Coggle Diagram
BRUGIA MALAYI
MORPHOLOGY
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The head is slightly swollen and has two circles of well-defined papillae. Female :8 cm long by 0.3 mm wide. Male: 2 cm long by 0.1 mm wide.
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LIFE CYCLE
In a human host, An infected mosquito injects third-stage filarial larvae onto the skin of the human host during a blood meal, where they penetrate the bite wound.
They form in adults and are commonly found in the lymphatic system. Female worms are 80 to 100 mm long and 0.24 to 0.30 mm in diameter, while males are 40 mm long and 100 mm wide.
Adults produce microfilariae that are sheathed and have a nocturnal periodicity, measuring 244 to 296 m by 7.5 to 10 m.
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In mosquito host, mosquito ingests the microfilariae during a blood meal.
After ingestion, the microfilariae lose their sheaths and some of them work their way through the wall of the proventriculus and cardiac portion of the mosquito's midgut and reach the thoracic muscles.
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The third-stage infective larvae migrate through the hemocoel to the mosquito's prosbocis and can infect another human when the mosquito takes a blood meal.
PATHOGENESIS
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Pathology - Adults live in lymphatic vessels of the arms and legs and cause elephantiasis in these regions
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