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CONIVAPTAN image - Coggle Diagram
CONIVAPTAN
CONTRAINDICATIONS
Severe renal impairment
Decreased blood volume
Severe liver disease
Cessation of urine production
Chronic heart failure
Osmotic central pontine myelinosis
Increased sodium level in the blood
MECHANISM OF ACTION
inhibit aquaresis or excretion of free water.
In the kidneys, AVPs activity(primarily at V2 receptors)
Is a non-peptide dual AVP V1A and V2 receptor antagonist.
STORAGE CONDITIONS
Store at 25 degrees Celsius
SIDE EFFECTS
Insomnia
Diarrhea
Headache
Vomiting
Mild fever
Increased urination
Mild thirst
Low potassium
ROUTE OF ADMINISTRATION
Intravenously
INDICATIONS
Reduces the level of hormone that regulates the balance of water and salt in the body.
Improves urine flow
Treat euvolemic hyponatremia
