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Alcohols (Pharmacology) - Coggle Diagram

- - - - Antidote in methanol and ethylene glycol poisoning
    - - Zero-order metabolism, duration depends on dose
    - - Multiple effects on neurotransmitter receptors, ion channels, and signaling pathways
    - - Toxicity: Acute, CNS depression and respiratory failure. Chronic, damage to many systems, including liver, pancreas gastrointestinal tract, and central and peripheral nervous systems. Interactions: Induction of CYP2E1 :arrow_up:conversion of acetaminophen to toxic metabolite
- - - - Essential vitamin required for synthesis of the coenzyme thiamine pyrophosphate
    - - Administered to patients suspected of alcohol dependence to prevent the Wernicke-Korsakoff syndrome
    - - Parenteral
        administration
    - - None
  - - - Antidote in methanol and
        ethylene glycol poisoning
    - - Multiple effects on neurotransmitter receptors ion channels, and signaling pathways
- - - - Reduced risk of relapse in individuals with alcohol use disorders
    - - Oral administration
    - - Poorly understood NMDA receptor antagonist and GABA A agonist effects
    - - Gastrointestinal effects and rash
  - - - Deterrent to relapse in individuals with alcohol use disorders
    - - Oral administration
    - - Inhibits aldehyde dehydrogenese
    - - Little effect on its own but
        severe flushing, headache ,nausea, vomiting, and hypotension when combined with ethanol
  - - - Reduced risk of relapse ini ndividuals with alcohol use disorders
    - - Available as an oral or long-acting parenteral formulation
    - - Nonselective competitive antagonist of opioid receptors
    - - Gastrointestinal effects and liver toxicity