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Nicola Ricci period 6 anatomy Immune and lymphatic systems - Coggle Diagram
Nicola Ricci period 6 anatomy Immune and lymphatic systems
Innate(natural)immune defenses and Adaptive(acquired)immune defenses
Innate immune defenses
chemical barriers
such as the highly acidic and caustic environment provided by gastric juice, or lysozyme in tears, kill many pathogens
Natural killer cells
a type of lymphocyte that defends the body against various viruses and cancer cells
mechanical barriers
it uses unbroken skin, and the mucous membranes of the body to create mechanical (physical) barriers that prevent the entry of certain pathogens.
inflammation
a tissue’s response to a pathogen, characterized by redness, swelling, heat, and pain
species resistance
a species is resistant to diseases that affect other species
phagocytosis
the most active phagocytes are neutrophils and monocytes, these leave the bloodstream at areas of injuries
Adaptive immune defenses
cell- mediated immunity
humoral immunity
Major functions of the Lymphatic & Immune systems
immune system
Inate defenses
chemical barriers
such as the highly acidic and caustic environment provided by gastric juice, or lysozyme in tears, kill many pathogens
natural killer cells
a type of lymphocyte that defends the body against various viruses and cancer cells
mechanical barriers
it uses unbroken skin, and the mucous membranes of the body to create mechanical (physical) barriers that prevent the entry of certain pathogens.
inflammation
a tissue’s response to a pathogen, characterized by redness, swelling, heat, and pain
species resistance
a species is resistant to diseases that affect other species
phagocytosis
the most active phagocytes are neutrophils and monocytes, these leave the bloodstream at areas of injuries
adaptive defenses
the response mounted by the body against specific recognized foreign molecules
lymphatic system
lymphatic vessels
carry away excess fluid
lacteals transport fat to the circulatory system
lymphatic organs
thymus
secretes a hormone called thymosins which regulate t-lymphocyte production
lymph nodes
the cells within the lymph nodes filter the waste particles in the lymph
spleen
filters blood and removes damaged cells and bacteria
Anatomy of the lymphatic system
lymphatic tissue
lymphatic nodules
Compact masses of lymphatic tissue
Tonsils
Appendix
lymphatic organs
lymph nodes
contains
lymphocytes
macrophages
located along lymphatic vessels
thymus
located behind the sternum and above the heart
surrounded by a connective tissue capsule that divides it into lobules
spleen
located in the upper left abdominal cavity
contains blood instead of lymph
white pulp contains many lymphocytes
red pulp contains red blood cells, macrophages, and lymphocytes
Humoral response and cellular response
cellular response
T cell activation requires the presence of an antigen presenting cell
in order for the T cell to be activated it must first encounter a macrophage displaying the antigen on its MHC
Activated T cells interact directly with antigen-bearing cells this is called cellular immune response
humoral response
B cells may become activated and produce a clone of cells when its antigen receptor encounters its matching antigen
when CD4 encounters a B cell that has encountered an antigen the CD4 releases cytokines so the B cell can divide and make clones.
Some of the B cells become plasma cells, creating antibodies, like T cells
Antigens and antibodies
Antigens
polysaccharides
glycoproteins
can all trigger an immune response
proteins
glycolipids
can be the whole pathogen or just a part of it
Antibodies
protein secreted from plasma cells
carried by body fluids, capable of binding specifically to antigens
5 major types of antibodies
IgG
Most abundant antibody in primary and secondary immune response
IgA
prevents attachment of pathogens to epithelial cells
IgM
first class of antibodies realeased by B cells during primary response
IgD
cell surface receptor of the mature B cell
IgE
when bound to antigens, it binds to mast cells and basophils to release histamine
Cells involved in the immune system
adaptive immunity
cell mediated
T lymphocytes
humoral mediated
B lymphocytes
inate defenses
natural killer cells
Disorders associated withthe Immunesystem
Edema (lymphatic filariasis)
fluids are not returned to the vascular system
elephantiasis
AIDS
lowers the amount of white blood cells in your body and can lead to other harmful effects