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Parkinson desease - Coggle Diagram
Parkinson desease
symptoms
reduced arm swinging, hand tremor, leg dragging.
the most common:
Tremor (trembling) in hands, arms, legs, jaw, or head.
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Impaired balance and coordination, sometimes leading to falls.
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curiosities 
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Evolution might thus have packed
the human brain with increased convergence of cortical projections to individual striatal neurons and nigrostriatal axons compared to other species.
The proposed cortical pathogenic
theory is built upon the increasing amount of evidence documenting cortical involvement in the early and prodromal stages of Parkinson’s disease.
Parkinson’s disease (PD) is the second most common neurode generative disorder after Alzheimer’s disease, with close to 5 million individuals affected worldwide and expectations for this number to double by 2030.
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Attentional orienting, therefore, is the mechanism through which we are in
able to select objects, events, places
control top-down includes parts of the intraparietal cortex and the superior frontal cortex and is involved in the targeted selection of stimuli and responses.
control bottom up appears
largely lateralized to the right hemisphere and includes the temporoparietal cortex and the inferior frontal cortex.
The two theories
are not mutually exclusive, in the sense that bottom-up and top-down mechanisms can in principle coexist, possibly
explaining the increasingly recognized complexity of predominant phenotypes and evolutions of Parkinson’s disease.
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