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Chapter 12: TRANSCRIPTION, rna modificaiton, EUKARYOTIC TRANSCRIPTION,…
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rna modificaiton
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Cleavage: RNA transcript is cleaved, eukaryotic rRNA and tRNA. one or more smaller pieces becomese functional
45S rRNA: 18S, 5.8S, 28S, form ribosome struvtture.
splicing: happens in premRNA, rRNA, tRNA
capping: eukaryotic mRNA, 7' meth added to 5' end of mRNA (beginning). splices introns, exits mRNA from nucleus, binds mRNA to ribosome
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EUKARYOTIC TRANSCRIPTION
THREE RNA enzymes
RNA Polymerase II: mRNA (protein encoding genes), snRNA (used for splicing)
12 subunits, catalyzees nucleotide linkage in 5' to 3' direction
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RNA Polymerase III: tRNA, 5S RNA, some snRNA
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RNA Polymerase I: ribosomal RNA, 45S rRNA(18S,5.8S,28S) except for 5S
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