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Non-Neoplasia - 5, image, 1-s2.0-S0917239414000044-gr1 - Coggle Diagram
Non-Neoplasia - 5
Odontogenic Cysts
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Most common type of odontogenic cyst, but it is an inflammatory cyst (not developmental). Higher incidence in males and it usually affects young adults
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microscopically, it is lined by cuboidal-squamous epithelium
If it is not removed, the cyst wall continues to enlarge
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Eruption cyst:
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most commonly associated with the deciduous mandibular central incisors and maxillary first permanent molars
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eruption hematoma: there is blood in the fluid, giving a purplish color to the tissue at the eruption site
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Odontogenic Keratocyst:
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The lumen is lined by thin corrugated squamous epithelium 8-10 cell-layers thick, prominent, palisaded basal cell layer with flat interface between epithelium & Connective tissue
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Well-defined, multilocular radiolucency
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Glandular cyst
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About 75% of cases are reported in the mandible (posterior) but it also affects the anterior portion of the maxilla
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Paget Disease of Bone
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Typically involves the pelvis, femur, spinal column, tibia, and skull. Maxilla is more commonly affected than the mandible.
Abnormal bone metabolism, including resorption, osteoblastic repair, and remineralization of the involved bone
Radiographic appearance is a patchy radiolucency and radiopacity; "cotton-wool" appearance. Hypercementosis and loss of lamina dura, and obliteration of PDL may also occur.
Clinically= enlargement of affected bone; pain. When maxilla or mandible are involved, spacing between the teeth increases as the bone enlarges; when edentulous, dentures no longer fit.
Diagnosis= clinical, radiographic, and histopathologic features. Laboratory evaluation of serum phosphatase level will be elevated in active disease.
Treatments= biosphosphonate zoledronic acid has been found to keep the disease in remission for up to 6 years. Other treatments involve osteoclast inhibitors.
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