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Autoregulation - Coggle Diagram
Autoregulation
Intrinsic Mechanism
MyogenicReflex
High systemic blood pressure
Excessive amount of filtration
smooth muscles of efferent arterioles stretches
Vasoconstriction
decreases amount of blood pressure
Low systemic blood pressure
Decrease in filtration rate
efferent arterioles smooth muscles dilates
Vasodilation
Increase of intrinsic blood pressure
TubuloglomerularFeedback Reflex
High GFR
Increase amount of filtrate
increase amount of NaCL molecules flows through the loop of Henle and distal tubules
influx of Na and Cl ions through Macula Densa, causes depolarization then ATP causes release of adenosine which causes release of Ca ions in the mesangial cells which stimulates release of renin enzyme from juxtaglomerular cells
Vasoconstriction
decrease in blood pressure
decrease in GHP
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Low GFR
low amount of Na and Cl in the filtrate
less Na and Cl flows through distal tubule
no influx of Na and Cl in Macula densa
inhibits depolarization, Adenosine release, Ca ions released renin release
relaxes the smooth muscles
vasodilation
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