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Biomedcial - Coggle Diagram
Biomedcial
Tomography- cross-sectional imaging on an object.
PET- Positron emission tomography
SPECT- single photon emission
MRI Magnetic resonance imaging (structural)
CT computed tomography (structural)
Tracking via tracer principle
minimising variables (involuntary / voluntary motion, stress)
Nanotechnology
Small particles (10^-9)
Use: Photothermal therapy (PTT) and photodynamic therapy (PDT)
High surface area to volume ratio
Odd properties due to size
In vivo cell culture, in vivo administration
in vivo, MPS issues
Ligands (causes lock and key binding)
Microfluids
Constant Laminar Flow vs Turbulent Flow
Methods of mixing fluids and droplet generation
Diffusion by random movement
Tesla and Square Elbows
Capillary, T and Y junctions
Manipulating generation
Faster flow = smaller droplets
Continuous Droplet PCR
Repairing damaged body parts
Challenging with cell growth
curing diseases
Tissue Engineering (reparation)
STEM Cells
Multipotent
Pluripotent
Hydrogels
biomaterial scaffold
Biomolecules (growth factors)
Protein
Lipid
Carbohydrates
Nucleic acids
Design and planning week 6
CAD drafts
Legends, materials
Identify solution
Technology for disabilities
Cerebral palsy- physical disability
GMFCS 1-5. 1-3 ambulant, 4-5 non ambulant
Neural interfaces
Improve life quality
intellectual vs physical disability
Physical disability- STEM cells and growth factors
Anatomy and physiology
Bone
Cells
Osteoblasts
Osteocytes
Compact bone
Muscle
Functions
Movement, posture
Support for tissue
Store nutrients
Neurons
Sensory
Sensory
Interneurons
Cardiovascular System
atriums
Ventricles
Biomaterials
Metallic
Polymer Base
Bioceramic
Biologically derived materials (skin, collagen)
Regulations
International standards
Records
DHF
Outputs - designs, BOM
verification records
inputs (documents)
Validation records
Risk management
project management
DMR
Specifications
Production Procedures
Equipment and environment requirements
Fluid dynamics and Bernoulli's equations
Bernoulli''s Principle: Conservation of kinetic, potential and pressure energy
Use in human body: circulatory system, respiratory system
bioelectronics
Solving problems of clinical needs using electronic devices
Examples
Near-Infrared Light Transmission
Myoelectric sensors
Bioelectronics in tissue engineering
Image reconstruction
modelling for wound
Biomechanics and Computational modelling
Solid modelling
Convert data and image to CAD model
Numerical analysis
Generate mesh
finite element analysis
Verify results
Data acquisition
Inspect region of interest
obtain required material properties
Medical recalls
Case studies
ProteGEN mesh
ASR hip replacement
Silicone implants
Biomedical manufacturing (biomanufacturing)
Enforce standards
ISO13485
Regulatory environment
produce valid results
Target approvals
guaranteed level of quality
Ethics
Ethical theories-Allows to view choice from multiple views
Rights
Ethical Egoism
Virtue
Utilitarianism
Duty
Career Options
Industry
Networking
Finding current problems
PHD
Self engaged Research
Neuromodulation and bionics
Neuromodulation
alteration of nerve activity (target delivery)
Examples
electrical stimulation
chemical agents
nervous system
Central NS
Peripheral NS
bionics
studies of brain via electronic equipment
devices
bionic eye
cochlear implant