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Biopsy - Coggle Diagram
Biopsy
intestinal
indications
chronic weight loss + good appetite
malabsorption suspects
PLE
chronic vomiting/diarrhea
diffuse intestinal thickening
negative exploratory
methods
surgical
full thickness
can do a full explore
unable to see mucosal surface
expensive
invasive
riskier
technique
wedge biopsy
longitudinal elliptical incision in antimesenteric side
transverse closure
punch biopsy
4mm
must cut mucosa with Metzenbaum
3 simp int sutures
don't punch through both sides :upside_down_face:
leak test
endoscopic
less invasive
mucosa only
limited
proximal duodenum
LI
rare to biopsy the colon
complications
not benign
10% mortality
dehiscence
septic peirtonitis
liver
methods
laparoscopic
larger samples
more expensive
more training required
general anesthesia req
open
punch
more hemorrhage
limit depth to less than half the thickness of lobe
use gelfoam
absorbs blood
structural support
guillotine
use vessel/tissue sealer
US-guided tru-cut
difficult to access liver in most animals
only 45% correlation with open