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PROTEIN MODIFICATIONS - Coggle Diagram
PROTEIN MODIFICATIONS
IRREVERSIBLE
ubiquitylation
ubiquitin attached to lysine
proteolysis
use of proteases
glycosylation
N-linked
O-linked
REVERSIBLE
phosphorylation/dephosphorylation
kinases
ATP independent
e.g. MAPK cascade, PI3K
enzyme-coupled receptors
phosphatases
ATP dependent
e.g. PTEN, PP2A
on Ser, Thr, Tyr
acetylation
histones
chromatin "relaxation"