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Cystic Fibrosis : - Coggle Diagram
Cystic Fibrosis :
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Incidence/Prevalence
Affects 1 in 17,000 African Americans
Affects 1 in 31,000 Asian Americans
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References
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Huether, S. & McCance, K. (2019). Understanding pathophysiology (7th edition). Elsevier health services
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Pathogenesis
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Chloride and water can’t be transported across these channels properly, resulting in abnormally thick and dehydrated mucus secretions
Impaired mucus clearance leads to bacterial infections, triggering chronic inflammatory responses that result in airway damage
Pulmonary vascular remodelling occurs over time and can lead to pulmonary hypertension and right-sided heart failure
Treatments
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Medications:
Bronchodilators: albuterol, Theophylline, and Ipratropium
Antibiotics: Ciprofloxacin, Tobramycin, Cephalexin
Mucolytics: Guaifenesin, DNase, N-acetylcysteine
Anti-inflammatories: Triamcinolone, Flunisolide, Fluticasone
Risk Factors
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Most commonly seen in Northern European ancestry, but can occur with other races.
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