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Canine and Feline Discoid Lupus Erythematosus - Coggle Diagram
Canine and Feline Discoid Lupus Erythematosus
general
2nd most common autoimmune skin disease in dogs
only affects skin
unknown pathogenesis
history
starts with depigmentation and erythema of nasal planum
crusts develop
licking, bleeding
aggravated by sunlight
otherwise healthy
lesions
depigmentation
erythema
erosins
ulcerations
crusting
scarring
distribution
nasal planum
extending to dorsal muzzle
mucocutaneous jxn
scrotum
ears
distal limbs
diagnosis
history and CS
cytology
no
acantholytic cells
skin biopsy for
histopathology
treatment
not life threatening
may wax and wane
topicals
corticosteroids
beware skin atrophy
tacrolimus
may need dog nose protector
systemic
severe or unresponsive cases
oral glucocorticoid
oral cyclosporine
oclacitinib/Apoquel
annecdotal
tetracycline + niacinamide
sunscreen