Please enable JavaScript.

Coggle requires JavaScript to display documents.

Lesson 13 - Coggle Diagram

- - - - Coagulate and denature proteins at high temperature
      - Steam has high penetrative power and moistens the spores, hence bacteria will be more susceptible
  - - - Interaction with water
        
        Formation of free radicals
        
        Damage microorganisms and DNA
        
        Cell lysis
      - Advantages
        
        Wide range of materials are compatible with
        radiation
      - Disadvantages
        
        High capital cost
      - Effects
        
        Chain scission
        
        Crosslinking of polymer chains
        
        Decrease mechanical properties
        
        Disrupt polymer chains
        
        Discoloration
        
        Decrease Glass Transition temperature
        
        Formation of warpage when exceeded decreased Tg
  - - - Precondition of the implant (24 hours) (Humidity at 60%)
        
        Treatment
        
        Apply vacuum to remove air
        
        Inject EtO gas to achieve 600mL-1200mL
        
        Temperature: 30-50°C
        
        Relative humidity: 40-90%
        
        Duration: 2-48 hours
    - - Compatible to a wide range of
        materials.
      - Sterilize fully packaged articles
    - - Toxic and potentially carcinogenic
      - Air pollution
      - Possibility of absorbing EtO during sterilization
- - - - HDPE is permeable towards EtO gas as well as water vapour
        
        Prevents a change in properties of HDPE
      - Prevents HDPE from discoloration
      - Prevents chain scission
    - - Use packaging material which can withstand high heat and pressure
      - Polycarbonate with Tg above 121kpa will not turn rubbery during autoclave